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Does #Neanderthal #DNA increase the #risk for severe #COVD-19 ?

The Neanderthal genome project is an effort of a group of scientists to sequence the Neanderthal genome, founded in July 2006.

It was initiated by 454 Life Sciences, a biotechnology company based in Branford, Connecticut in the United States and is coordinated by the Max Planck Institute for Evolutionary Anthropology in Germany. In May 2010 the project published their initial draft of the Neanderthal genome based on the analysis of four billion base remain in modern humans outside Africa.

In December 2013, a high coverage genome of a Neanderthal was reported for the first time. It stemmed from a Neanderthal female bone fragment found in a cave in the Altai mountains of Siberia from around 50,000–100,000 years ago.

As per the press release from Max Planck Institute for Evolutionary Anthropology. - 'A segment of DNA that causes their carriers to have an up to three times higher risk of developing severe Covid-19 is inherited from Neandertals.'

'Covid-19 affects some people much more severely than others. Some reasons for this such as old age are already known, but other as yet unknown factors also play a role. This summer, a large international study linked a group of genes on chromosome 3 to a higher risk of hospitalisation and respiratory failure upon infection with the Sars-CoV-2 virus. Researchers at the Karolinska Institutet in Sweden and the Max Planck Institute for Evolutionary Anthropology in Germany have now analysed the gene cluster.'



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